Job Number HT-455 Process Development Associate - Temporary
Functional Area: Protein Sciences Maxygen, Inc. is committed to the discovery, development and commercialization of improved next-generation protein pharmaceuticals for the treatment of disease and serious medical conditions. We have a great pipeline of clinical candidates through our joint ventureship with Astellas, which we have named Perseid Therapeutics. We still have great people, ample resources and a serious, but fun working environment. We offer access to and use of cutting-edge technology and the opportunity to work with other great people.
There is an immediate opening within our Protein Sciences/Process Development Department for an experienced individual with the background, talents and interests listed below. This position is a temporary position and could very well last for six or more months. If you are interested in applying for this position, please email your resume/CV to jobs@maxygen.com and be sure to include "HT-455 in the subject line of the email. Thanks! We look forward to hearing from you!
In this position, you will be by supplying different quantities and qualities of purified proteins to a variety of Perseid projects that are in the discovery and development stages.
1. The position entails the execution of a variety of purification procedures.
2. Perform column chromatography on AKTA HPLC equipment (e.g. AKTA Explorer, AKTA Pilot). The understanding of the basic principles of protein chromatography, e.g. using hydroxyapatite, AIEX, CIEX, SEC, ProtA, would be beneficial.
3. Operate automated and semi-automated tangential flow filtration equipment (e.g. AKTA Crossflow, Sartorius Tandem).
4. Perform the typical post run analytics (e.g. SDS-PAGE, GPC, UV spectroscopy) and handle samples that are going to be submitted to the analytical group.
5. Diligently document experimental work in notebooks and possibly contribute to the generation of SOPs and reports. Qualifications: Must have a BS/BA in Biochemistry, Analytical Chemistry or related discipline with at least 2 years of biotechnology industry experience or an MS in Biochemistry, Analytical Chemistry or related discipline. Additionally, would prefer:
1. Experience with the development of column chromatography procedures for purification of proteins/biopharmaceuticals at the milligram to gram scale
2. Knowledge in the use of the above mentioned equipment
3. Good verbal and written communication skills are important. The candidate must be able to efficiently handle rapidly shifting work tasks in a highly collaborative team environment.
4. The candidate should be well organized, have a strong work ethic and be diligent in data documentation.
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